Humanized Anti-Human CD3 mAb
Catalog Number: TL-101
Product name
Generic names: Humanized Anti-Human CD3 mAb
Product information
Species Reactivity: Human
Specificity: Recognizes the εchain of the CD3/T cell antigen receptor complex (McMichael, A.J. et al. (1987) Leucocyte Typing III: White Cell Differentiation Antigens, Oxford University Press,New York; Knapp, W. et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens,Oxford University Press, New York; Schlossman, S. et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York).
Source: CHO cells
QC Testing Purity: > 95 % as determined by SDS-PAGE
Purification: Protein A purified from cell culture supernatant
Immunogen: Recombinant human CD3
Endotoxin Level: <0.1 EU/μg
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with HSA
Stability & Storage: Samples are stable for up to 24 months from date of receipt at 4 ℃. Avoid repeated freeze-thaw cycles.
Applications: 1. ELISA(recommended concentration 1:5000-1:10000) 2. T Cell Stimulation: This antibody can be used to activate T cells when immobilized at 1-10μg/mL (100 μL/well)
Background
CD3 is one of at least four invariant proteins that associate with the variable antigen recognition chains of the T cell recep tor and function in signal transduction.
References
1. Beverly, P.C.L. and R.E. Callard (1981) Eur. J. Immunol. 11:329.
Trial dosage: A customer can apply for up to five samples a year (the actual trial dosage is determined by telephone or email communication).
Scope of use: Samples are limited to testing and research purposes.
Cost: Free for samples, customer is responsible for shipping and handling charges, reference cost is $50 in the US, €60 in the EU, and $50 in other countries.
How to apply: You can apply by telephone or by email (the email application should specify the sample name, item number, contact person, telephone number, consignee address, etc.).
